BDBM372449 3,5-diamino-N-(N-(4-(4-((S)-3-amino-2-(3-(hexyl((2S,3R,4R,5R)-2,3,4,5,6-pentahydroxyhexyl)amino)propylamino)-3-oxopropyl)-5,6,7,8-tetrahydronaphthalen-1-yl)butyl)carbamimidoyl)-6-chloropyrazine-2-carboxamide::US10246425, Compound XII-d

SMILES CCCCCCN(CCCN[C@@H](Cc1ccc(CCCCNC(=N)NC(=O)c2nc(Cl)c(N)nc2N)c2CCCCc12)C(N)=O)C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO

InChI Key InChIKey=VVTLXIJXSUOICC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 372449   

TargetSodium channel protein type 5 subunit alpha(Human)
Parion Sciences

US Patent
LigandPNGBDBM372449(US10246425, Compound XII-d | 3,5-diamino-N-(N-(4-(...)
Affinity DataIC50: 8.40nMAssay Description:One assay used to assess mechanism of action and/or potency of the compounds of the present invention involves the determination of lumenal drug inhi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
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