BDBM3728 6-(Dimethylamino)-4-[(3-methylphenyl)amino]pyrido[3,4-d]pyrimidine::6-N,6-N-dimethyl-4-N-(3-methylphenyl)pyrido[3,4-d]pyrimidine-4,6-diamine::PD158780 Analog 9c

SMILES CN(C)c1cc2c(Nc3cccc(C)c3)ncnc2cn1

InChI Key InChIKey=SSOSNGLIBSWZMG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 3728   

TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3728(6-N,6-N-dimethyl-4-N-(3-methylphenyl)pyrido[3,4-d]...)
Affinity DataIC50: 2.80nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2005
Entry Details Article
PubMed