BDBM373087 1-(3-methyl-1- phenyl-1H-pyrazol- 5-yl)-3-naphthalen- 1-ylurea::US9896447, Compound 4

SMILES Cc1cc(NC(=O)Nc2cccc3ccccc23)n(n1)-c1ccccc1

InChI Key InChIKey=ITUONRMWMXHWAX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 373087   

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM373087(1-(3-methyl-1- phenyl-1H-pyrazol- 5-yl)-3-naphthal...)
Affinity DataIC50: 590nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent