BDBM373094 1-(5- methoxypyridin-2- yl)-3-(3-methyl-1- phenyl-1H-pyrazol- 5-yl)urea::US9896447, Compound 11

SMILES COc1ccc(NC(=O)Nc2cc(C)nn2-c2ccccc2)nc1

InChI Key InChIKey=MXFFRUHGCGVJIS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 373094   

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM373094(1-(5- methoxypyridin-2- yl)-3-(3-methyl-1- phenyl-...)
Affinity DataIC50: 3.40E+3nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent