BDBM373102 1-(2-methyl-4- phenylpyrimidin-5- yl)-3-(2-phenyl-1H- indol-3-yl)urea::US9896447, Compound 19

SMILES Cc1ncc(NC(=O)Nc2c([nH]c3ccccc23)-c2ccccc2)c(n1)-c1ccccc1

InChI Key InChIKey=NKCDLEBSRGHVOM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 373102   

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM373102(1-(2-methyl-4- phenylpyrimidin-5- yl)-3-(2-phenyl-...)
Affinity DataIC50: 570nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent