BDBM373110 1-[3-(1-methyl-1H- imidazol-2- yl)phenyl]-3-(2- phenylimidazo[1,2- a]pyridin-3-yl)urea::US9896447, Compound 27

SMILES Cn1ccnc1-c1cccc(NC(=O)Nc2c(nc3ccccn23)-c2ccccc2)c1

InChI Key InChIKey=SZNHNIQVPBEZEE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 373110   

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM373110(1-[3-(1-methyl-1H- imidazol-2- yl)phenyl]-3-(2- ph...)
Affinity DataIC50: 1.60E+3nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent