BDBM373114 1-(6-chloro-2- phenylimidazo[1,2- b]pyridazin-3-yl)-3- (2- phenylimidazo[1,2- a]pyridin-3-yl)urea::US9896447, Compound 31

SMILES Clc1ccc2nc(c(NC(=O)Nc3c(nc4ccccn34)-c3ccccc3)n2n1)-c1ccccc1

InChI Key InChIKey=HMAIFVBYZMDSHE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 373114   

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM373114(1-(6-chloro-2- phenylimidazo[1,2- b]pyridazin-3-yl...)
Affinity DataIC50: 1.00E+3nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent