BDBM373115 N-methyl-3-{[(2- phenylimidazo[1,2- a]pyridin-3- yl)carbamoyl] amino}imidazo[1,2- a]pyridine-2- carboxamide::US9896447, Compound 32

SMILES CNC(=O)c1nc2ccccn2c1NC(=O)Nc1c(nc2ccccn12)-c1ccccc1

InChI Key InChIKey=YJCUREVCXBNDRN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 373115   

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM373115(N-methyl-3-{[(2- phenylimidazo[1,2- a]pyridin-3- y...)
Affinity DataIC50: 1.00E+3nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent