BDBM373117 1-(1,2-dimethyl-4- phenyl-1H-imidazol- 5-yl)-3-(2-methyl-4- phenyl-1,3-thiazol- 5-yl)urea::US9896447, Compound 34

SMILES Cc1nc(c(NC(=O)Nc2c(nc(C)n2C)-c2ccccc2)s1)-c1ccccc1

InChI Key InChIKey=UHOAFSGYZRZVFV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 373117   

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM373117(1-(1,2-dimethyl-4- phenyl-1H-imidazol- 5-yl)-3-(2-...)
Affinity DataIC50: 4.10E+3nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent