BDBM373121 1-[5-fluoro-2- (trifluoromethyl) benzyl]-3-(1-phenyl- 1H- pyrazol-5-yl)urea::US9896447, Compound 38

SMILES Fc1ccc(c(CNC(=O)Nc2ccnn2-c2ccccc2)c1)C(F)(F)F

InChI Key InChIKey=ICUJVTNVXFQXEM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 373121   

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM373121(1-[5-fluoro-2- (trifluoromethyl) benzyl]-3-(1-phen...)
Affinity DataIC50: 1.10E+3nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent