BDBM373129 1-(1-phenyl-1H- pyrazol-5-yl)-3-{2- [(trifluoromethyl) sulfanyl]benzyl}urea::US9896447, Compound 44

SMILES FC(F)(F)Sc1ccccc1CNC(=O)Nc1ccnn1-c1ccccc1

InChI Key InChIKey=CHQLNSNKCDXIKC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 373129   

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM373129(1-(1-phenyl-1H- pyrazol-5-yl)-3-{2- [(trifluoromet...)
Affinity DataIC50: 420nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent