BDBM373130 1-(5-methyl-3- phenylisoxazol-4- yl)-3-{2- [(trifluoromethyl) sulfanyl]benzyl}urea::US9896447, Compound 45

SMILES Cc1onc(c1NC(=O)NCc1ccccc1OC(F)(F)F)-c1ccccc1

InChI Key InChIKey=ZQKJYWSBBRQRMR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 373130   

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM373130(1-(5-methyl-3- phenylisoxazol-4- yl)-3-{2- [(trifl...)
Affinity DataIC50: 420nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent