BDBM373131 1-(1-methyl-5- phenyl-1H-pyrazol- 4-yl)-3-[2- (trifluoromethoxy) benzyl]urea::US9896447, Compound 46

SMILES Cn1ncc(NC(=O)NCc2ccccc2OC(F)(F)F)c1-c1ccccc1

InChI Key InChIKey=HFHSZNLNQMXZPH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 373131   

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM373131(1-(1-methyl-5- phenyl-1H-pyrazol- 4-yl)-3-[2- (tri...)
Affinity DataIC50: 1.60E+3nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent