BDBM373203 US9896452, Example 63::rac-N-(((2S,3R)-1-(5-(4-fluorophenyl)-2-methylthiazole-4-carbonyl)-3-methylpiperidin-2-yl)methyl)benzofuran-4-carboxamide

SMILES C[C@@H]1CCCN([C@@H]1CNC(=O)c1cccc2occc12)C(=O)c1nc(C)sc1-c1ccc(F)cc1

InChI Key InChIKey=MMZJCOGZVWFSAF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 373203   

TargetOrexin/Hypocretin receptor type 1(Human)
Eolas Therapeutics

US Patent
LigandPNGBDBM373203(rac-N-(((2S,3R)-1-(5-(4-fluorophenyl)-2-methylthia...)
Affinity DataIC50: 2nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO-OX1 or CHO-OX2 cells are seeded into black-walled clear-base 384-well plates (Costar) at a density of 20,00...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

TargetOrexin receptor type 2(Human)
Eolas Therapeutics

US Patent
LigandPNGBDBM373203(rac-N-(((2S,3R)-1-(5-(4-fluorophenyl)-2-methylthia...)
Affinity DataIC50: 48nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO-OX1 or CHO-OX2 cells are seeded into black-walled clear-base 384-well plates (Costar) at a density of 20,00...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent