BDBM373538 US9903855, Molecule 5

SMILES OC(=O)CCCCCN1C(=O)N\C(=C/c2c(NCc3ccco3)nc3ccccn3c2=O)C1=O

InChI Key InChIKey=UTCYYEKLSXFISX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 373538   

TargetInhibitor of nuclear factor kappa-B kinase subunit epsilon(Human)
University of California

US Patent
LigandPNGBDBM373538(US9903855, Molecule 5)
Affinity DataIC50: 1.00E+4nMAssay Description:Please see Hutti, et al., (2012). Development of a High-Throughput Assay for Identifying Inhibitors of TBK1 and IKKε.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase TBK1(Human)
University of California

US Patent
LigandPNGBDBM373538(US9903855, Molecule 5)
Affinity DataIC50: 870nMAssay Description:Please see Hutti, et al., (2012). Development of a High-Throughput Assay for Identifying Inhibitors of TBK1 and IKKε.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
Go to US Patent

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
University of California

US Patent
LigandPNGBDBM373538(US9903855, Molecule 5)
Affinity DataIC50: 1.00E+4nMAssay Description:Please see Hutti, et al., (2012). Development of a High-Throughput Assay for Identifying Inhibitors of TBK1 and IKKε.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
Go to US Patent

TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
University of California

US Patent
LigandPNGBDBM373538(US9903855, Molecule 5)
Affinity DataIC50: 1.00E+4nMAssay Description:Please see Hutti, et al., (2012). Development of a High-Throughput Assay for Identifying Inhibitors of TBK1 and IKKε.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
Go to US Patent