BDBM3745 N-(3-bromophenyl)-5-methyl-5H-pyrimido[5,4-b]indol-4-amine::Pyrimido[5,4-b]indole deriv. 36

SMILES Cn1c2ccccc2c2ncnc(Nc3cccc(Br)c3)c12

InChI Key InChIKey=ULWYMPIRZLVNFN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 3745   

TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3745(N-(3-bromophenyl)-5-methyl-5H-pyrimido[5,4-b]indol...)
Affinity DataIC50: 132nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2005
Entry Details Article
PubMed