BDBM374637 1-((R)-1-(2,4-Dichlorophenyl)ethyl)-6-((2S)-2,5-dimethyl-4-(pyrrolidin-1-yl)piperidin-1-yl)-3-methyl-1H-pyrazolo[3,4-b]pyrazine hydrochloride::US10246462, Example 18

SMILES C[C@H](c1ccc(Cl)cc1Cl)n1nc(C)c2ncc(nc12)N1CC(C)C(C[C@@H]1C)N1CCCC1

InChI Key InChIKey=URHNEDINMDEFPG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 374637   

TargetC-C chemokine receptor type 4(Human)
Flx Bio

US Patent
LigandPNGBDBM374637(US10246462, Example 18 | 1-((R)-1-(2,4-Dichlorophe...)
Affinity DataIC50: 300nMAssay Description:To measure binding of 125I-TARC or 125I-MDC to cells expressing CCR4 (e.g., CEM cells (e.g., ATCC HB-12624)), the 125I-TARC or 125I-MDC is diluted to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent