BDBM374880 US10251893, Cpd 108::US10251893, Cpd 84

SMILES Cc1cc(ccn1)-c1ccc(CC(=O)Nc2ccc(nc2)-c2cccc(F)c2)cn1

InChI Key InChIKey=ZQRZZEMDEQTZRC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 374880   

TargetProtein Wnt-3a(Human)
Novartis

US Patent
LigandPNGBDBM374880(US10251893, Cpd 84 | US10251893, Cpd 108)
Affinity DataIC50: 0.200nMAssay Description:Human embryonic kidney 293 cells (obtained from American Type Culture Collection, ATCC, Manassas, Va.) are cultured in DMEM medium (Gibco/Invitrogen,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

TargetProtein Wnt-3a(Human)
Novartis

US Patent
LigandPNGBDBM374880(US10251893, Cpd 84 | US10251893, Cpd 108)
Affinity DataIC50: 128nMAssay Description:Human embryonic kidney 293 cells (obtained from American Type Culture Collection, ATCC, Manassas, Va.) are cultured in DMEM medium (Gibco/Invitrogen,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent