BDBM375174 N-(2-{[(1S)-1-(6-chloro-2-::US10253015, Compound I-34

SMILES C[C@H](Nc1nccc(NC(C)=O)c1F)c1cc2cc(Cl)ccc2[nH]c1=O

InChI Key InChIKey=JILJRTQNPBPZLZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 375174   

LigandPNGBDBM375174(N-(2-{[(1S)-1-(6-chloro-2- | US10253015, Compound ...)
Affinity DataIC50: 10nMAssay Description:Assays were performed in a 384-well black plate. An aliquot of 250 nL of compound was incubated with 10 μL of 30 nM IDH1-R132H or 10 nM IDH1-R13...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
Go to US Patent

LigandPNGBDBM375174(N-(2-{[(1S)-1-(6-chloro-2- | US10253015, Compound ...)
Affinity DataIC50: 55nMAssay Description:Assays were performed in a 384-well black plate. An aliquot of 250 nL of compound was incubated with 10 μL of 30 nM IDH1-R132H or 10 nM IDH1-R13...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
Go to US Patent