BDBM37518 MLS000074703::N-[2-(tert-butylamino)-2-keto-ethyl]-N-(2-thenyl)thiadiazole-4-carboxamide::N-[2-(tert-butylamino)-2-oxidanylidene-ethyl]-N-(thiophen-2-ylmethyl)-1,2,3-thiadiazole-4-carboxamide::N-[2-(tert-butylamino)-2-oxoethyl]-N-(thiophen-2-ylmethyl)-4-thiadiazolecarboxamide::N-[2-(tert-butylamino)-2-oxoethyl]-N-(thiophen-2-ylmethyl)thiadiazole-4-carboxamide::SMR000006321::[1,2,3]Thiadiazole-4-carboxylic acid (tert-butylcarbamoyl-methyl)-thiophen-2-ylmethyl-amide::cid_644558

SMILES CC(C)(C)NC(=O)CN(Cc1cccs1)C(=O)c1csnn1

InChI Key InChIKey=RKXFARUMORPDJC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 37518   

TargetHuntingtin(Human)
Columbia University Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM37518(N-[2-(tert-butylamino)-2-oxoethyl]-N-(thiophen-2-y...)
Affinity DataIC50: 8.00E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2011
Entry Details
PCBioAssay