BDBM375261 US10253018, Example 27

SMILES CC(C)n1cnnc1-c1cccc(NC(=O)c2ccc3ccc(nc3c2)N2CCN(CC2)C(C)(C)C)n1

InChI Key InChIKey=DNKMUEQXSSLCLR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 375261   

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Enanta Pharmaceuticals

US Patent
LigandPNGBDBM375261(US10253018, Example 27)
Affinity DataIC50: 1.00E+3nMAssay Description:ASK1 was purchased from Thermofisher (Catalogue # PV4011), ATP was purchased from Sigma (Catalogue # A7699), HTRF KinEASE Assay System was obtained f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent