BDBM375271 US10253018, Example 37

SMILES CC(C)n1cnnc1-c1cccc(NC(=O)c2ccc3cc(cnc3c2)-c2ccc(cc2)C(C)(C)C)n1

InChI Key InChIKey=VSZKTNOZQVVSJT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 375271   

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Enanta Pharmaceuticals

US Patent
LigandPNGBDBM375271(US10253018, Example 37)
Affinity DataIC50: 1.00E+3nMAssay Description:ASK1 was purchased from Thermofisher (Catalogue # PV4011), ATP was purchased from Sigma (Catalogue # A7699), HTRF KinEASE Assay System was obtained f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent