BDBM375694 US9908895, Example 68

SMILES C[C@@H](N)c1nc2cnc3ccsc3c2n1[C@H]1CC[C@H](CC#N)OC1

InChI Key InChIKey=MEYXZFYNDTXKRD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 375694   

TargetTyrosine-protein kinase JAK1(Human)
Incyte

US Patent
LigandPNGBDBM375694(US9908895, Example 68)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2020
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Incyte

US Patent
LigandPNGBDBM375694(US9908895, Example 68)
Affinity DataIC50: 2.00E+3nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2020
Entry Details
US Patent