BDBM37573 MLS000044182::N-[1-(cyclopentylcarbamoyl)cyclohexyl]-N-(2-furfuryl)-6-keto-1H-pyridine-3-carboxamide::N-[1-(cyclopentylcarbamoyl)cyclohexyl]-N-(furan-2-ylmethyl)-6-oxidanylidene-1H-pyridine-3-carboxamide::N-[1-(cyclopentylcarbamoyl)cyclohexyl]-N-(furan-2-ylmethyl)-6-oxo-1H-pyridine-3-carboxamide::N-[1-[(cyclopentylamino)-oxomethyl]cyclohexyl]-N-(2-furanylmethyl)-6-oxo-1H-pyridine-3-carboxamide::N-{1-[(cyclopentylamino)carbonyl]cyclohexyl}-N-(2-furylmethyl)-6-oxo-1,6-dihydropyridine-3-carboxamide::SMR000021966::cid_3245326

SMILES O=C(NC1CCCC1)C1(CCCCC1)N(Cc1ccco1)C(=O)c1ccc(=O)[nH]c1

InChI Key InChIKey=RRJIRTWOFIYMHL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 37573   

TargetHuntingtin(Human)
Columbia University Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM37573(SMR000021966 | N-[1-(cyclopentylcarbamoyl)cyclohex...)
Affinity DataIC50: 8.00E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2011
Entry Details
PCBioAssay