BDBM375770 US10301323, Compound F4::US9908899, Compound F4

SMILES Nc1ccccc1NC(=O)c1ccc(CC2CN(Cc3ccc4cc[nH]c4c3)C2)cc1

InChI Key InChIKey=OOIHAYFWFNCYQM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 375770   

TargetHistone deacetylase 1(Human)
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM375770(US10301323, Compound F4 | US9908899, Compound F4)
Affinity DataIC50: 1.00E+3nMAssay Description:The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2020
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM375770(US10301323, Compound F4 | US9908899, Compound F4)
Affinity DataIC50: 1.00E+3nMAssay Description:The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
US Patent

TargetHistone deacetylase 3(Human)
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM375770(US10301323, Compound F4 | US9908899, Compound F4)
Affinity DataIC50: 1.00E+3nMAssay Description:The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2020
Entry Details
US Patent

TargetHistone deacetylase 3(Human)
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM375770(US10301323, Compound F4 | US9908899, Compound F4)
Affinity DataIC50: 1.00E+3nMAssay Description:The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
US Patent