BDBM37589 2-(2-keto-2-pyrrolidino-ethyl)-4H-1,4-benzoxazin-3-one::2-(2-oxidanylidene-2-pyrrolidin-1-yl-ethyl)-4H-1,4-benzoxazin-3-one::2-(2-oxo-2-pyrrolidin-1-ylethyl)-4H-1,4-benzoxazin-3-one::2-[2-oxo-2-(1-pyrrolidinyl)ethyl]-4H-1,4-benzoxazin-3-one::MLS000119415::SMR000096336::cid_5308640

SMILES O=C(CC1Oc2ccccc2NC1=O)N1CCCC1

InChI Key InChIKey=LZMKCTVLJCZBAQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 37589   

TargetHuntingtin(Human)
Columbia University Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM37589(2-(2-oxo-2-pyrrolidin-1-ylethyl)-4H-1,4-benzoxazin...)
Affinity DataIC50: 8.00E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2011
Entry Details
PCBioAssay