BDBM376026 N-{5'-methyl-3-[2-oxo-2- (pyridin-2-ylamino)ethyl]-2'H- 1,3'-bipyrazol-5-yl}-3-(1- methyl-1H-pyrazol-3-yl)-4- (trifluoromethyl)benzamide::US9914736, Compound 22

SMILES Cc1cc([nH]n1)-n1nc(CC(=O)Nc2ccccn2)cc1NC(=O)c1ccc(c(c1)-c1ccn(C)n1)C(F)(F)F

InChI Key InChIKey=BODJCQQDLYRZJT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 376026   

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM376026(US9914736, Compound 22 | N-{5'-methyl-3-[2-oxo-2- ...)
Affinity DataIC50: 5.60nMAssay Description: In this assay, U2OS cells express the human TrkA receptor as a fusion with the weakly complementing fragment of B-galactosidase, which DiscoverX cal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details
US Patent