BDBM3765 12-nitro-N-[3-(trifluoromethyl)phenyl]-8-thia-3,5-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,5,10,12-hexaen-6-amine::Benzothieno[3,2-d]pyrimidine deriv. 56

SMILES [O-][N+](=O)c1ccc2sc3c(Nc4cccc(c4)C(F)(F)F)ncnc3c2c1

InChI Key InChIKey=XUMLPLGHKIPVJA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 3765   

TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3765(12-nitro-N-[3-(trifluoromethyl)phenyl]-8-thia-3,5-...)
Affinity DataIC50: 460nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2005
Entry Details Article
PubMed