BDBM378783 N-(1-((1-benzyl-1H-pyrazol-4-yl)methyl)azetidin-3-yl)-4-cyclopropylpicolinamide::US10266526, Compound 966

SMILES O=C(NC1CN(Cc2cnn(Cc3ccccc3)c2)C1)c1cc(ccn1)C1CC1

InChI Key InChIKey=PMULBZYSTIEGHU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 378783   

TargetN-lysine methyltransferase SMYD2(Human)
Epizyme

US Patent
LigandPNGBDBM378783(US10266526, Compound 966 | N-(1-((1-benzyl-1H-pyra...)
Affinity DataIC50: 13nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% Bovine Skin Gelatin, and 0.002% Tween20, prepared on...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2020
Entry Details
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