BDBM378874 US10266535, Compound 2

SMILES Nc1ncnc2n(nc(-c3ccc(Oc4ccccc4)cc3)c12)[C@@H]1CCCN(C1)C(=O)C(F)(F)F

InChI Key InChIKey=RKJKBBWFGYJCGL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 378874   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Hefei Institutes of Physical Science, Chinese Academy of Sciences

US Patent
LigandPNGBDBM378874(US10266535, Compound 2)
Affinity DataIC50: 572nMAssay Description:In the experiments of in vitro enzymatic activity, the IC50 values of Compound 33, Compound 30, Compound 14, Compound 20, Compound 22, Compound 23, C...More data for this Ligand-Target Pair
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Date in BDB:
2/7/2020
Entry Details
US Patent