BDBM380550 N-[trans-4-(3- fluoroazetidin-1- yl)cyclohexyl]-6- methylquinazolin- 4-amine::US9926330, 2-3

SMILES Cc1ccc2ncnc(N[C@H]3CC[C@@H](CC3)N3CC(F)C3)c2c1

InChI Key InChIKey=JIDDHNOKRRFMJW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 380550   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM380550(US9926330, 2-3 | N-[trans-4-(3- fluoroazetidin-1- ...)
Affinity DataIC50: 94nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
US Patent