BDBM380552 4-{trans-4-[(6- methylquinazolin- 4- yl)amino]cyclo- hexyl}piperazin-2- one::US9926330, 2-5

SMILES Cc1ccc2ncnc(N[C@H]3CC[C@@H](CC3)N3CCNC(=O)C3)c2c1

InChI Key InChIKey=ANRQTULIJSJWDL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 380552   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM380552(US9926330, 2-5 | 4-{trans-4-[(6- methylquinazolin-...)
Affinity DataIC50: 113nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
US Patent