BDBM380572 US9926330, 2-25::trans-N- (cyclopropylmethyl)-N'-(6- methylquinazolin-4- yl)cyclohexane-1,4- diamine

SMILES Cc1ccc2ncnc(N[C@H]3CC[C@@H](CC3)NCC3CC3)c2c1

InChI Key InChIKey=IJLDLXZWJGFINS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 380572   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM380572(US9926330, 2-25 | trans-N- (cyclopropylmethyl)-N'-...)
Affinity DataIC50: 31nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
US Patent