BDBM380580 N'-(6-ethenylquinazolin-4-yl)-N,N- dimethylcyclohexane-1,4-diamine::US9926330, 3-2

SMILES CN(C)C1CCC(CC1)Nc1ncnc2ccc(C=C)cc12

InChI Key InChIKey=WCCUWRRSCSLTIT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 380580   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM380580(US9926330, 3-2 | N'-(6-ethenylquinazolin-4-yl)-N,N...)
Affinity DataIC50: 7nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
US Patent