BDBM380585 N,N-dimethyl-N'-[6-(1- methylethyl)quinazolin-4- yl]cyclohexane-1,4-diamine::US9926330, 4-2

SMILES CC(C)c1ccc2ncnc(NC3CCC(CC3)N(C)C)c2c1

InChI Key InChIKey=NVCNSCNNTAXPPA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 380585   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM380585(US9926330, 4-2 | N,N-dimethyl-N'-[6-(1- methylethy...)
Affinity DataIC50: 16nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
US Patent