BDBM381084 US9890185, Example 38(g)

SMILES COc1c(NC(=O)Nc2ccc(Oc3ccnc(NCc4ccccc4)n3)c3ccccc23)cc(cc1P(C)(C)=O)C(C)(C)C

InChI Key InChIKey=UHIRRHIZJMTBGU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 381084   

TargetMitogen-activated protein kinase 14(Human)
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US Patent
LigandPNGBDBM381084(US9890185, Example 38(g))
Affinity DataIC50: 9nMAssay Description:Method 1: The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen), are evaluated indirectly by determinin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
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US Patent
LigandPNGBDBM381084(US9890185, Example 38(g))
Affinity DataIC50: 2.37E+3nMAssay Description:Method 1: The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
US Patent