BDBM381259 4-Chloro-1,3-dimethyl-1H- pyrazolo[3,4-b]pyridine-5- carboxylic acid (3-bromo-phenyl)- amide::US10272074, Example 92

SMILES Cc1nn(C)c2ncc(C(=O)Nc3cccc(Br)c3)c(Cl)c12

InChI Key InChIKey=ACJSXMNPDIFMLN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 381259   

TargetGlucocorticoid receptor(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM381259(4-Chloro-1,3-dimethyl-1H- pyrazolo[3,4-b]pyridine-...)
Affinity DataIC50: 50nMAssay Description:The assay was performed using H4 neuroglioma cells and using indirect immunofluorescence detection of the endogenous GR receptor. Fixative: 4% PFA. P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details
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