BDBM381310 4-Chloro-1-ethyl-3-methyl-1H- pyrazolo[3,4-b]pyridine-5- carboxylic acid (4-isopropyl- phenyl)-amide::US10272074, Example 143

SMILES CCn1nc(C)c2c(Cl)c(cnc12)C(=O)Nc1ccc(cc1)C(C)C

InChI Key InChIKey=YXIDNTWABUQDTN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 381310   

TargetGlucocorticoid receptor(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM381310(4-Chloro-1-ethyl-3-methyl-1H- pyrazolo[3,4-b]pyrid...)
Affinity DataIC50: 50nMAssay Description:The assay was performed using H4 neuroglioma cells and using indirect immunofluorescence detection of the endogenous GR receptor. Fixative: 4% PFA. P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details
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