BDBM381320 4-Chloro-1-(3-methoxy-propyl)-3- methyl-1H-pyrazolo[3,4- b]pyridine-5-carboxylic acid (4- trifluoromethyl-phenyl)-amide::US10272074, Example 153

SMILES COCCCn1nc(C)c2c(Cl)c(cnc12)C(=O)Nc1ccc(cc1)C(F)(F)F

InChI Key InChIKey=NDRMKROFQGSFQL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 381320   

TargetGlucocorticoid receptor(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM381320(4-Chloro-1-(3-methoxy-propyl)-3- methyl-1H-pyrazol...)
Affinity DataIC50: 50nMAssay Description:The assay was performed using H4 neuroglioma cells and using indirect immunofluorescence detection of the endogenous GR receptor. Fixative: 4% PFA. P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details
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