BDBM38169 (S)-3-(5-Oxo-4,5-dihydro-1H-tetrazol-1-yl)-4-(p-tolyl)-6-(4-(4,4,4-trifluorobutoxy)phenyl)-6-(trifluoromethyl)-5,6-dihydropyridin-2(1H)-one::US10093650, Example 1::US10329273, Example 1

SMILES COc1ccc(Cn2nnn(CC(=O)NC(CC(=O)c3ccc(C)cc3)(c3ccc(OCCCC(F)(F)F)cc3)C(F)(F)F)c2=O)cc1

InChI Key InChIKey=WAMSPWDUTZPPPH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 38169   

LigandPNGBDBM38169(US10093650, Example 1 | (S)-3-(5-Oxo-4,5-dihydro-1...)
Affinity DataIC50: 27nMpH: 7.4Assay Description:The MGAT enzyme reactions were performed in Corning FALCON 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
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LigandPNGBDBM38169(US10093650, Example 1 | (S)-3-(5-Oxo-4,5-dihydro-1...)
Affinity DataIC50: 27nMAssay Description:The MGAT enzyme reactions were performed in Corning FALCON 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
Go to US Patent