BDBM381916 US10272095, Example 78::rel-(S)-3-(1,4-Dimethyl- 1H-benzo[d][1,2,3]triazol- 5-yl)-3-(rel-(S)-3-(2,2- dimethyl-2,3- dihydrobenzo[f][1,4] oxazepin-4(5H)-yl)-2,3- dihydro-1H-inden-5-yl)- 2,2-dimethylpropanoic acid

SMILES Cc1c(ccc2n(C)nnc12)[C@H](c1ccc2CC[C@H](N3Cc4ccccc4OC(C)(C)C3)c2c1)C(C)(C)C(O)=O

InChI Key InChIKey=WTUWJHPLITTXLD-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 381916   

TargetNAD(P)H dehydrogenase [quinone] 1(Human)
Glaxosmithkline

US Patent
LigandPNGBDBM381916(rel-(S)-3-(1,4-Dimethyl- 1H-benzo[d][1,2,3]triazol...)
Affinity DataEC50:  5.5nMAssay Description:NAD(P)H:quinone oxidoreductase 1 (NQO1), also called DT diaphorase, is a homodimeric FAD-containing enzyme that catalyzes obligatory NAD(P)H-dependen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details
US Patent