BDBM382157 1-((5-((trans-4-(trifluoromethyl)cyclohexyl)oxy)naphthalen-2-yl)methyl)azetidine-3-carboxylic acid::US10273234, Example 20

SMILES OC(=O)C1CN(Cc2ccc3c(O[C@H]4CC[C@@H](CC4)C(F)(F)F)cccc3c2)C1

InChI Key InChIKey=JHEJKCOKOVYSPW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 382157   

TargetAutotaxin(Human)
Biogen Ma

US Patent
LigandPNGBDBM382157(US10273234, Example 20 | 1-((5-((trans-4-(trifluor...)
Affinity DataIC50: 2.75E+3nMAssay Description:ATX (Autotaxin) is a 125 KDa glycoprotein with lysophospholipase D (LPLD) activity that generates the bioactive lipid lysophosphatidic acid (LPA) fro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details
US Patent