BDBM382361 US10273259, Example 74

SMILES OC(=O)C12CCC(CC1)(CC2)C(=O)N1CCC2(C1CCc1cc(ccc21)C(F)(F)C(F)F)S(=O)(=O)c1ccc(F)cc1

InChI Key InChIKey=FOQPAUJPHCQMGZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 382361   

TargetNuclear receptor ROR-gamma(Mouse)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM382361(US10273259, Example 74)
Affinity DataIC50: 18nMAssay Description:The binding of potential ligands to RORγ is measured by competition with [3H]25-hydroxycholesterol (Perkin Elmer NET674250UC) using a scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details
US Patent