BDBM382444 US10273223, Compound D-51

SMILES CNCCN1CCC(CC1)c1cc(C(=O)NCC2=C(C)C=C(C)NC2C)c2cnn(C3CCCC3)c2c1

InChI Key InChIKey=UDVVVEXQJIEUNO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 382444   

TargetHistone-lysine N-methyltransferase EZH2(Human)
Epizyme

US Patent
LigandPNGBDBM382444(US10273223, Compound D-51)
Affinity DataIC50: 300nMAssay Description:eneral Procedure for Wild-Type PRC2 Enzyme Assay on Oligonucleosome Substrate. The assays was performed in a buffer consisting of 20 mM bicine (pH=7....More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details
US Patent