BDBM383431 2-cyano-N-(((5R,8S)-3-(2,6- difluorophenyl)-9,9-dimethyl- 5,6,7,8-tetrahydro-5,8- methanocinnolin-8-yl)methyl)-N- ethylbenzenesulfonamide::US10280144, Compound 147

SMILES CCN(C[C@@]12CC[C@@H](c3cc(nnc13)-c1c(F)cccc1F)C2(C)C)S(=O)(=O)c1ccccc1C#N

InChI Key InChIKey=GNUNCUVZECGCQB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 383431   

TargetNuclear receptor ROR-gamma(Human)
Genentech

US Patent
LigandPNGBDBM383431(2-cyano-N-(((5R,8S)-3-(2,6- difluorophenyl)-9,9-di...)
Affinity DataIC50: 3.60nMAssay Description:Consumable Supplier and product code GFB Unifilter plates Perkin Elmer 6005177 3-[(3- Sigma C5070 Cholamidopropyl)dimethylammonio]- 1-propanesulfonat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2020
Entry Details
US Patent