BDBM383505 US10280149, Example 10::[(3S)-1-cyclopentyl-3-piperidyl]-(6-methoxy-2-naphthyl)methanone

SMILES COc1ccc2cc(ccc2c1)C(=O)[C@H]1CCCN(C1)C1CCCC1

InChI Key InChIKey=JNSVKSRNLAOUJI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 383505   

TargetLysine-specific demethylase 2B(Human)
Genentech

US Patent
LigandPNGBDBM383505([(3S)-1-cyclopentyl-3-piperidyl]-(6-methoxy-2-naph...)
Affinity DataIC50: 56.6nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
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Date in BDB:
2/21/2020
Entry Details
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