BDBM383557 US10280149, Example 66::[1-(3,3-difluorocyclobutyl)-3-piperidyl]-(6-methoxy-2-naphthyl)methanone

SMILES COc1ccc2cc(ccc2c1)C(=O)C1CCCN(C1)C1CC(F)(F)C1

InChI Key InChIKey=JRYMSOZKLGEFQC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 383557   

TargetLysine-specific demethylase 2B(Human)
Genentech

US Patent
LigandPNGBDBM383557([1-(3,3-difluorocyclobutyl)-3-piperidyl]-(6-methox...)
Affinity DataIC50: 67.5nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2020
Entry Details
Go to US Patent