BDBM383559 US10280149, Example 68::[4-(1-hydroxyethyl)-2-naphthyl]-(1-propyl-3-piperidyl)methanone

SMILES CCCN1CCCC(C1)C(=O)c1cc(C(C)O)c2ccccc2c1

InChI Key InChIKey=BUXHPJZADADCRI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 383559   

TargetLysine-specific demethylase 2B(Human)
Genentech

US Patent
LigandPNGBDBM383559([4-(1-hydroxyethyl)-2-naphthyl]-(1-propyl-3-piperi...)
Affinity DataIC50: 76.2nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
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Date in BDB:
2/21/2020
Entry Details
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