BDBM383654 (1-(cyclopropylmethyl)-4-methylpiperidin-3-yl)(5-hydroxynaphthalen-2-yl)methanone::US10280149, Example 151b

SMILES C[C@H]1CCN(CC2CC2)C[C@H]1C(=O)c1ccc2c(O)cccc2c1

InChI Key InChIKey=ANKHEAPBRVNMCP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 383654   

TargetLysine-specific demethylase 2B(Human)
Genentech

US Patent
LigandPNGBDBM383654((1-(cyclopropylmethyl)-4-methylpiperidin-3-yl)(5-h...)
Affinity DataIC50: 39.5nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
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Date in BDB:
2/21/2020
Entry Details
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