BDBM383672 6-(4-methyl-1-propylpiperidine-3-carbonyl)-2-naphthonitrile::US10280149, Example 163b

SMILES CCCN1CC[C@@H](C)[C@@H](C1)C(=O)c1ccc2cc(ccc2c1)C#N

InChI Key InChIKey=QBUTTZRSWPBBLI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 383672   

TargetLysine-specific demethylase 2B(Human)
Genentech

US Patent
LigandPNGBDBM383672(6-(4-methyl-1-propylpiperidine-3-carbonyl)-2-napht...)
Affinity DataIC50: 45.4nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
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Date in BDB:
2/21/2020
Entry Details
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